PDB Information

PDB2RD0
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations.
Huang, C.H., Mandelker, D., Schmidt-Kittler, O., Samuels, Y., Velculescu, V.E., Kinzler, K.W., Vogelstein, B., Gabelli, S.B., Amzel, L.M.
Science
HeaderTransferase/Oncoprotein
Released2007-09-20
Resolution3.050
CATH Insert Date27 Dec, 2007

PDB Images (10)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 27 Dec, 2007 Chopped
B 27 Dec, 2007 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
2rd0A01 22 Sep, 2008 3.10.20.90 Assigned
2rd0A02 22 Sep, 2008 3.10.20.90 Assigned
2rd0A03 22 Sep, 2008 2.60.40.150 Assigned
2rd0A04 22 Sep, 2008 1.25.40.70 Assigned
2rd0A05 22 Sep, 2008 3.30.1010.10 Assigned
2rd0A06 22 Sep, 2008 1.10.1070.11 Assigned
2rd0B00 22 Sep, 2008 1.10.287.1490 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27986 P85A_HUMAN Homo sapiens Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336 PK3CA_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
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