PDB Information

PDB2QHM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.
Brnardic, E.J., Garbaccio, R.M., Fraley, M.E., Tasber, E.S., Steen, J.T., Arrington, K.L., Dudkin, V.Y., Hartman, G.D., Stirdivant, S.M., Drakas, B.A., Rickert, K., Walsh, E.S., Hamilton, K., Buser, C.A., Hardwick, J., Tao, W., Beck, S.C., Mao, X., Lobell, R.B., Sepp-Lorenzino, L., Yan, Y., Ikuta, M., Munshi, S.K., Kuo, L.C., Kreatsoulas, C.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-07-02
Resolution2.000
CATH Insert Date20 Mar, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 20 Mar, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2qhmA01 21 Mar, 2008 3.30.200.20 Assigned
2qhmA02 21 Mar, 2008 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1
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