PDB Information

PDB2Q6C
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
Pfefferkorn, J.A., Choi, C., Song, Y., Trivedi, B.K., Larsen, S.D., Askew, V., Dillon, L., Hanselman, J.C., Lin, Z., Lu, G., Robertson, A., Sekerke, C., Auerbach, B., Pavlovsky, A., Harris, M.S., Bainbridge, G., Caspers, N.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2007-06-04
Resolution2.000
CATH Insert Date19 Jul, 2007

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 19 Jul, 2007 Chopped
B 19 Jul, 2007 Chopped
C 19 Jul, 2007 Chopped
D 19 Jul, 2007 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2q6cA01 16 Aug, 2007 1.10.3270.10 Assigned
2q6cA02 16 Aug, 2007 3.90.770.10 Assigned
2q6cA03 16 Aug, 2007 3.30.70.420 Assigned
2q6cB01 17 Aug, 2007 1.10.3270.10 Assigned
2q6cB02 17 Aug, 2007 3.90.770.10 Assigned
2q6cB03 17 Aug, 2007 3.30.70.420 Assigned
2q6cC01 17 Aug, 2007 1.10.3270.10 Assigned
2q6cC02 17 Aug, 2007 3.90.770.10 Assigned
2q6cC03 17 Aug, 2007 3.30.70.420 Assigned
2q6cD01 17 Aug, 2007 1.10.3270.10 Assigned
2q6cD02 17 Aug, 2007 3.90.770.10 Assigned
2q6cD03 17 Aug, 2007 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
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