PDB 2q2y

PDB Information

PDB2Q2Y
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
Roecker, A.J., Coleman, P.J., Mercer, S.P., Schreier, J.D., Buser, C.A., Walsh, E.S., Hamilton, K., Lobell, R.B., Tao, W., Diehl, R.E., South, V.J., Davide, J.P., Kohl, N.E., Yan, Y., Kuo, L.C., Li, C., Fernandez-Metzler, C., Mahan, E.A., Prueksaritanont, T., Hartman, G.D.
Bioorg.Med.Chem.Lett.
HeaderCell Cycle
Released2007-05-29
Resolution2.500
CATH Insert Date07 Nov, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
B 08 Nov, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2q2yA00 23 Nov, 2007 3.40.850.10 Assigned
2q2yB00 23 Nov, 2007 3.40.850.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P52732 KIF11_HUMAN Homo sapiens Kinesin-like protein KIF11
P52732 KIF11_HUMAN Homo sapiens Kinesin-like protein KIF11