PDB Information

PDB2OJ9
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R).
Velaparthi, U., Wittman, M., Liu, P., Stoffan, K., Zimmermann, K., Sang, X., Carboni, J., Li, A., Attar, R., Gottardis, M., Greer, A., Chang, C.Y., Jacobsen, B.L., Sack, J.S., Sun, Y., Langley, D.R., Balasubramanian, B., Vyas, D.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-01-12
Resolution2.000
CATH Insert Date03 May, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 May, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2oj9A01 31 Mar, 2009 3.30.200.20 Assigned
2oj9A02 31 Mar, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
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