PDB 2oht

PDB Information

PDB2OHT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
Congreve, M., Aharony, D., Albert, J., Callaghan, O., Campbell, J., Carr, R.A., Chessari, G., Cowan, S., Edwards, P.D., Frederickson, M., McMenamin, R., Murray, C.W., Patel, S., Wallis, N.
J.Med.Chem.
HeaderHydrolase
Released2007-01-10
Resolution2.300
CATH Insert Date15 Mar, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Mar, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ohtA01 16 Jul, 2007 2.40.70.10 Assigned
2ohtA02 16 Jul, 2007 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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