PDB Information

PDB2OGZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site.
Sheehan, S.M., Mest, H.J., Watson, B.M., Klimkowski, V.J., Timm, D.E., Cauvin, A., Parsons, S.H., Shi, Q., Canada, E.J., Wiley, M.R., Ruehter, G., Evers, B., Petersen, S., Blaszczak, L.C., Pulley, S.R., Margolis, B.J., Wishart, G.N., Renson, B., Hankotius, D., Mohr, M., Zechel, J.C., Michael Kalbfleisch, J., Dingess-Hammond, E.A., Boelke, A., Weichert, A.G.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-01-09
Resolution2.100
CATH Insert Date15 Mar, 2007

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Mar, 2007 Chopped
B 15 Mar, 2007 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2ogzA01 14 Jul, 2007 3.40.50.1820 Assigned
2ogzA02 14 Jul, 2007 2.140.10.30 Assigned
2ogzB01 14 Jul, 2007 3.40.50.1820 Assigned
2ogzB02 14 Jul, 2007 2.140.10.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
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