PDB Information

PDB2NTR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites.
McGaughey, G.B., Colussi, D., Graham, S.L., Lai, M.T., Munshi, S.K., Nantermet, P.G., Pietrak, B., Rajapakse, H.A., Selnick, H.G., Stauffer, S.R., Holloway, M.K.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2006-11-08
Resolution1.800
CATH Insert Date15 Nov, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ntrA01 29 Nov, 2007 2.40.70.10 Assigned
2ntrA02 29 Nov, 2007 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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