PDB 2irw

PDB	2IRW
Method	X-RAY DIFFRACTION
Host Organism
Gene Source	Homo sapiens
Primary Citation	Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation. Patel, J.R., Shuai, Q., Dinges, J., Winn, M., Pliushchev, M., Fung, S., Monzon, K., Chiou, W., Wang, J., Pan, L., Wagaw, S., Engstrom, K., Kerdesky, F.A., Longenecker, K., Judge, R., Qin, W., Imade, H.M., Stolarik, D., Beno, D.W., Brune, M., Chovan, L.E., Sham, H.L., Jacobson, P., Link, J.T. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase
Released	2006-10-16
Resolution	3.100
CATH Insert Date	23 Feb, 2007

PDB 2irw

PDB Chain 2irwA

PDB Chain 2irwB

PDB Chain 2irwC

PDB Chain 2irwD

PDB Chain 2irwE

PDB Chain 2irwF

PDB Chain 2irwG

PDB Chain 2irwH

CATH Domain 2irwA00

CATH Domain 2irwB00

CATH Domain 2irwC00

CATH Domain 2irwD00

CATH Domain 2irwE00

CATH Domain 2irwF00

CATH Domain 2irwG00

CATH Domain 2irwH00

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2irwA00	05 Dec, 2008	3.40.50.720	Assigned
2irwB00	05 Dec, 2008	3.40.50.720	Assigned
2irwC00	05 Dec, 2008	3.40.50.720	Assigned
2irwD00	05 Dec, 2008	3.40.50.720	Assigned
2irwE00	05 Dec, 2008	3.40.50.720	Assigned
2irwF00	05 Dec, 2008	3.40.50.720	Assigned
2irwG00	05 Dec, 2008	3.40.50.720	Assigned
2irwH00	05 Dec, 2008	3.40.50.720	Assigned

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1