PDB Information

PDB2IEJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase.
Eastman, R.T., White, J., Hucke, O., Yokoyama, K., Verlinde, C.L., Hast, M.A., Beese, L.S., Gelb, M.H., Rathod, P.K., Van Voorhis, W.C.
Mol.Biochem.Parasitol.
HeaderTransferase
Released2006-09-19
Resolution1.800
CATH Insert Date23 Feb, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Feb, 2007 Chopped
B 23 Feb, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2iejA00 13 Jul, 2007 1.25.40.120 Assigned
2iejB00 13 Jul, 2007 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49356 FNTB_HUMAN Homo sapiens Protein farnesyltransferase subunit beta
P49354 FNTA_HUMAN Homo sapiens Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
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