PDB Information

PDB2GU8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies
Lin, X., Murray, J.M., Rico, A.C., Wang, M.X., Chu, D.T., Zhou, Y., Del Rosario, M., Kaufman, S., Ma, S., Fang, E., Crawford, K., Jefferson, A.B.
Bioorg.Med.Chem.Lett.
HeaderSignaling Protein,Transferase/Inhibitor
Released2006-04-28
Resolution2.200
CATH Insert Date03 May, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 May, 2007 Chopped
C 03 May, 2007 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2gu8A01 08 Dec, 2008 1.10.510.10 Assigned
2gu8A02 08 Dec, 2008 3.30.200.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P17612 KAPCA_HUMAN Homo sapiens cAMP-dependent protein kinase catalytic subunit alpha
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