PDB Information

PDB2GJX
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Crystallographic structure of human beta-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of GM2 Ganglioside Hydrolysis
Lemieux, M.J., Mark, B.L., Cherney, M.M., Withers, S.G., Mahuran, D.J., James, M.N.G.
J.Mol.Biol.
HeaderHydrolase
Released2006-03-31
Resolution2.800
CATH Insert Date14 Jul, 2006

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
C 14 Jul, 2006 Chopped
D 14 Jul, 2006 Chopped
E 14 Jul, 2006 Chopped
F 14 Jul, 2006 Chopped
G 14 Jul, 2006 Chopped
H 14 Jul, 2006 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
2gjxA01 15 Dec, 2006 3.30.379.10 Assigned
2gjxA02 15 Dec, 2006 3.20.20.80 Assigned
2gjxB01 15 Dec, 2006 3.30.379.10 Assigned
2gjxB02 15 Dec, 2006 3.20.20.80 Assigned
2gjxC01 16 Oct, 2006 3.30.379.10 Assigned
2gjxC02 16 Oct, 2006 3.20.20.80 Assigned
2gjxD01 14 Dec, 2006 3.30.379.10 Assigned
2gjxD02 14 Dec, 2006 3.20.20.80 Assigned
2gjxE01 15 Dec, 2006 3.30.379.10 Assigned
2gjxE02 15 Dec, 2006 3.20.20.80 Assigned
2gjxF01 14 Dec, 2006 3.30.379.10 Assigned
2gjxF02 14 Dec, 2006 3.20.20.80 Assigned
2gjxG01 15 Dec, 2006 3.30.379.10 Assigned
2gjxG02 15 Dec, 2006 3.20.20.80 Assigned
2gjxH01 15 Dec, 2006 3.30.379.10 Assigned
2gjxH02 15 Dec, 2006 3.20.20.80 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P06865 HEXA_HUMAN Homo sapiens Beta-hexosaminidase subunit alpha
P06865 HEXA_HUMAN Homo sapiens Beta-hexosaminidase subunit alpha
P07686 HEXB_HUMAN Homo sapiens Beta-hexosaminidase subunit beta
P07686 HEXB_HUMAN Homo sapiens Beta-hexosaminidase subunit beta
P07686 HEXB_HUMAN Homo sapiens Beta-hexosaminidase subunit beta
P06865 HEXA_HUMAN Homo sapiens Beta-hexosaminidase subunit alpha
P07686 HEXB_HUMAN Homo sapiens Beta-hexosaminidase subunit beta
P06865 HEXA_HUMAN Homo sapiens Beta-hexosaminidase subunit alpha