PDB Information

PDB2FJP
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Edmondson, S.D., Mastracchio, A., Mathvink, R.J., He, J., Harper, B., Park, Y.J., Beconi, M., Di Salvo, J., Eiermann, G.J., He, H., Leiting, B., Leone, J.F., Levorse, D.A., Lyons, K., Patel, R.A., Patel, S.B., Petrov, A., Scapin, G., Shang, J., Roy, R.S., Smith, A., Wu, J.K., Xu, S., Zhu, B., Thornberry, N.A., Weber, A.E.
J.Med.Chem.
HeaderHydrolase
Released2006-01-03
Resolution2.400
CATH Insert Date14 Jul, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2fjpA01 01 Nov, 2006 3.40.50.1820 Assigned
2fjpA02 01 Nov, 2006 2.140.10.30 Assigned
2fjpB01 02 Nov, 2006 3.40.50.1820 Assigned
2fjpB02 02 Nov, 2006 2.140.10.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
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