PDB 2f7e

PDB Information

PDB2F7E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceBos taurus
Primary Citation
Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Li, Q., Woods, K.W., Thomas, S., Zhu, G.D., Packard, G., Fisher, J., Li, T., Gong, J., Dinges, J., Song, X., Abrams, J., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Des Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2005-11-30
Resolution2.000
CATH Insert Date14 Jul, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
E 14 Jul, 2006 Chopped
I 14 Jul, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2f7eE01 28 Nov, 2006 1.10.510.10 Assigned
2f7eE02 28 Nov, 2006 3.30.200.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00517 KAPCA_BOVIN Bos taurus cAMP-dependent protein kinase catalytic subunit alpha