PDB Information

PDB2F4J
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.
Young, M.A., Shah, N.P., Chao, L.H., Seeliger, M., Milanov, Z.V., Biggs, W.H., Treiber, D.K., Patel, H.K., Zarrinkar, P.P., Lockhart, D.J., Sawyers, C.L., Kuriyan, J.
Cancer Res.
HeaderTransferase
Released2005-11-23
Resolution1.910
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2f4jA01 15 Mar, 2006 3.30.200.20 Assigned
2f4jA02 15 Mar, 2006 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00519 ABL1_HUMAN Homo sapiens Tyrosine-protein kinase ABL1
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