PDB 2c8z

PDB Links
Overview

PDB Information

PDB	2C8Z
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors Howard, N., Abell, C., Blakemore, W., Chessari, G., Congreve, M., Howard, S., Jhoti, H., Murray, C.W., Seavers, L.C.A., Van Montfort, R.L.M. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2005-12-08
Resolution	2.140
CATH Insert Date	18 Jul, 2006

PDB Images (6)

Image of CATH 2c8z

2c8z

PDB 2c8z

Image of CATH 2c8zA

2c8zA

PDB Chain 2c8zA

Image of CATH 2c8zB

2c8zB

PDB Chain 2c8zB

Image of CATH 2c8zI

2c8zI

PDB Chain 2c8zI

Image of CATH 2c8zB01

2c8zB01

CATH Domain 2c8zB01

Image of CATH 2c8zB02

2c8zB02

CATH Domain 2c8zB02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	18 Jul, 2006	Rejected
B	18 Jul, 2006	Chopped
I	18 Jul, 2006	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2c8zB01	18 Oct, 2006	2.40.10.10	Assigned
2c8zB02	18 Oct, 2006	2.40.10.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P00734	THRB_HUMAN	Homo sapiens	Prothrombin
P00734	THRB_HUMAN	Homo sapiens	Prothrombin
P09945	HIRV2_HIRME	Hirudo medicinalis	Hirudin variant-2