PDB 2c8y

PDB Links
Overview

PDB Information

PDB	2C8Y
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors Howard, N., Abell, C., Blakemore, W., Chessari, G., Congreve, M., Howard, S., Jhoti, H., Murray, C.W., Seavers, L.C.A., Van Montfort, R.L.M. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2005-12-08
Resolution	2.200
CATH Insert Date	18 Jul, 2006

PDB Images (6)

Image of CATH 2c8y

2c8y

PDB 2c8y

Image of CATH 2c8yA

2c8yA

PDB Chain 2c8yA

Image of CATH 2c8yB

2c8yB

PDB Chain 2c8yB

Image of CATH 2c8yI

2c8yI

PDB Chain 2c8yI

Image of CATH 2c8yB01

2c8yB01

CATH Domain 2c8yB01

Image of CATH 2c8yB02

2c8yB02

CATH Domain 2c8yB02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	18 Jul, 2006	Rejected
B	18 Jul, 2006	Chopped
I	18 Jul, 2006	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2c8yB01	18 Oct, 2006	2.40.10.10	Assigned
2c8yB02	18 Oct, 2006	2.40.10.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P00734	THRB_HUMAN	Homo sapiens	Prothrombin
P09945	HIRV2_HIRME	Hirudo medicinalis	Hirudin variant-2
P00734	THRB_HUMAN	Homo sapiens	Prothrombin