PDB 2c2z

PDB Information

PDB2C2Z
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
Ekici, O.D., Li, Z.Z., Campbell, A.J., James, K.E., Asgian, J.L., Mikolajczyk, J., Salvesen, G.S., Ganesan, R., Jelakovic, S., Grutter, M.G., Powers, J.C.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2005-10-02
Resolution1.950
CATH Insert Date28 Sep, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Sep, 2006 Chopped
B 28 Sep, 2006 Chopped
C 01 Aug, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2c2zA00 16 Oct, 2006 3.40.50.1460 Assigned
2c2zB00 16 Oct, 2006 3.30.70.1470 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q14790 CASP8_HUMAN Homo sapiens Caspase-8
Q14790 CASP8_HUMAN Homo sapiens Caspase-8
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