PDB Information

PDB2C2M
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
Ekici, O.D., Li, Z.Z., Campbell, A.J., James, K.E., Asgian, J.L., Mikolajczyk, J., Salvesen, G.S., Ganesan, R., Jelakovic, S., Grutter, M.G., Powers, J.C.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2005-09-29
Resolution1.940
CATH Insert Date28 Sep, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Sep, 2006 Chopped
B 28 Sep, 2006 Chopped
C 01 Aug, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2c2mA00 16 Oct, 2006 3.40.50.1460 Assigned
2c2mB00 16 Oct, 2006 3.30.70.1470 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P42574 CASP3_HUMAN Homo sapiens Caspase-3
P42574 CASP3_HUMAN Homo sapiens Caspase-3
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