PDB Information

PDB2BXT
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker
Bulat, S., Bosio, S., Papadopoulos, M.A., Cerezo-Galvez, S., Grabowski, E., Rosenbaum, C., Matassa, V.G., Ott, I., Metz, G., Schamberger, J., Sekul, R., Feurer, A.
Lett.Drug Des.Discovery
HeaderHydrolase/Hydrolase Inhibitor
Released2005-07-27
Resolution1.830
CATH Insert Date02 Nov, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 02 Nov, 2006 Chopped
I 02 Nov, 2006 Rejected
L 02 Nov, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2bxtH01 21 Jul, 2007 2.40.10.10 Assigned
2bxtH02 21 Jul, 2007 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin