PDB Information

PDB2B8L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Conformationally biased P3 amide replacements of beta-secretase inhibitors
Stachel, S.J., Coburn, C.A., Steele, T.G., Crouthamel, M.C., Pietrak, B.L., Lai, M.T., Holloway, M.K., Munshi, S.K., Graham, S.L., Vacca, J.P.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2005-10-07
Resolution1.700
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2b8lA01 10 Mar, 2006 2.40.70.10 Assigned
2b8lA02 10 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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