PDB Information

PDB2B7D
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Factor VIIa inhibitors: Chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model.
Young, W.B., Mordenti, J., Torkelson, S., Shrader, W.D., Kolesnikov, A., Rai, R., Liu, L., Hu, H., Leahy, E.M., Green, M.J., Sprengeler, P.A., Katz, B.A., Yu, C., Janc, J.W., Elrod, K.C., Marzec, U.M., Hanson, S.R.
Bioorg.Med.Chem.Lett.
HeaderBlood Clotting
Released2005-10-04
Resolution2.240
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 15 Mar, 2006 Chopped
L 15 Mar, 2006 Chopped
T 15 Mar, 2006 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
2b7dH01 22 Oct, 2006 2.40.10.10 Assigned
2b7dH02 22 Oct, 2006 2.40.10.10 Assigned
2b7dL01 17 Mar, 2006 2.10.25.10 Assigned
2b7dL02 17 Mar, 2006 2.10.25.10 Assigned
2b7dT00 17 Mar, 2006 2.60.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P13726 TF_HUMAN Homo sapiens Tissue factor
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII