PDB Information

PDB1ZKN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Crystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-Methylxanthine Suggest a Conformation Determinant of Inhibitor Selectivity
Huai, Q., Liu, Y., Francis, S.H., Corbin, J.D., Ke, H.
J.Biol.Chem.
HeaderHydrolase
Released2005-05-03
Resolution2.100
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1zknA00 10 Mar, 2006 1.10.1300.10 Assigned
1zknB00 10 Mar, 2006 1.10.1300.10 Assigned
1zknC00 10 Mar, 2006 1.10.1300.10 Assigned
1zknD00 10 Mar, 2006 1.10.1300.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
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