PDB Information

PDB1XS7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase).
Ghosh, A.K., Devasamudram, T., Hong, L., Dezutter, C., Xu, X., Weerasena, V., Koelsch, G., Bilcer, G., Tang, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2004-10-18
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
D 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1xs7D01 09 Mar, 2006 2.40.70.10 Assigned
1xs7D02 09 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1