PDB Information

PDB1U72
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.
Cody, V., Luft, J.R., Pangborn, W.
Acta Crystallogr.,Sect.D
HeaderOxidoreductase
Released2004-08-02
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1u72A00 09 Mar, 2006 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase
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