PDB Information

PDB1TU6
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with improved pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions
Barrett, D.G., Catalano, J.G., Deaton, D.N., Hassell, A.M., Long, S.T., Miller, A.B., Miller, L.R., Shewchuk, L.M., Wells-Knecht, K.J., Willard, D.H., Wright, L.L.
BIOORG.MED.CHEM.LETT.
HeaderHydrolase
Released2004-06-24
Resolution1.750
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1tu6A00 05 Mar, 2006 3.90.70.10 Assigned
1tu6B00 09 Mar, 2006 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P43235 CATK_HUMAN Homo sapiens Cathepsin K
P43235 CATK_HUMAN Homo sapiens Cathepsin K
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