PDB 1ta2

PDB Information

PDB1TA2
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position
Tucker, T.J., Brady, S.F., Lumma, W.C., Lewis, S.D., Gardel, S.J., Naylor-Olsen, A.M., Yan, Y., Sisko, J.T., Stauffer, K.J., Lucas, B.Y., Lynch, J.J., Cook, J.J., Stranieri, M.T., Holahan, M.A., Lyle, E.A., Baskin, E.P., Chen, I.-W., Dancheck, K.B., Krueger, J.A., Cooper, C.M., Vacca, J.P.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2004-05-19
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1ta2A01 05 Mar, 2006 2.40.10.10 Assigned
1ta2A02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P28504 HIR2_HIRME Hirudo medicinalis Hirudin-2
P00734 THRB_HUMAN Homo sapiens Prothrombin
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