PDB Information

PDB1SC7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
Staker, B.L., Feese, M.D., Cushman, M., Pommier, Y., Zembower, D., Stewart, L., Burgin, A.B.
J.Med.Chem.
HeaderIsomerase/Dna
Released2004-02-11
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 15 Mar, 2006 Rejected
C 15 Mar, 2006 Rejected
D 15 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1sc7A01 09 Mar, 2006 2.170.11.10 Assigned
1sc7A02 09 Mar, 2006 1.10.10.41 Assigned
1sc7A03 09 Mar, 2006 3.90.15.10 Assigned
1sc7A04 09 Mar, 2006 1.10.132.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11387 TOP1_HUMAN Homo sapiens DNA topoisomerase 1
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