PDB Information

PDB1SBG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 BH10
Primary Citation
An orally bioavailable HIV-1 protease inhibitor containing an imidazole-derived peptide bond replacement: crystallographic and pharmacokinetic analysis.
Abdel-Meguid, S.S., Metcalf, B.W., Carr, T.J., Demarsh, P., DesJarlais, R.L., Fisher, S., Green, D.W., Ivanoff, L., Lambert, D.M., Murthy, K.H.M., Petteway Jr., S.R., Pitts, W.J., Tomaszek Jr., T.A., Winborne, E., Zhao, B., Dreyer, G.B., Meek, T.D.
Biochemistry
HeaderHydrolase(Acid Protease)
Released1994-05-24
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1sbgA00 05 Mar, 2006 2.40.70.10 Assigned
1sbgB00 05 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
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