PDB 1sa5

PDB Links
Overview

PDB Information

PDB	1SA5
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Rattus norvegicus
Primary Citation	Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity. Reid, T.S., Beese, L.S. Biochemistry
Header	Transferase
Released	2004-02-06
Resolution	2.600
CATH Insert Date	05 Mar, 2006

PDB Images (5)

Image of CATH 1sa5

1sa5

PDB 1sa5

Image of CATH 1sa5A

1sa5A

PDB Chain 1sa5A

Image of CATH 1sa5B

1sa5B

PDB Chain 1sa5B

Image of CATH 1sa5A00

1sa5A00

CATH Domain 1sa5A00

Image of CATH 1sa5B00

1sa5B00

CATH Domain 1sa5B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1sa5A00	05 Mar, 2006	1.25.40.120	Assigned
1sa5B00	05 Mar, 2006	1.50.10.20	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q04631	FNTA_RAT	Rattus norvegicus	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Q02293	FNTB_RAT	Rattus norvegicus	Protein farnesyltransferase subunit beta