PDB 1s63
PDB Information
| PDB | 1S63 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes.
Biochemistry
|
| Header | Transferase |
| Released | 2004-01-22 |
| Resolution | 1.900 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Prints
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Mar, 2006 | Chopped |
| B | 05 Mar, 2006 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 1s63A00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s63B00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P49354 | FNTA_HUMAN | Homo sapiens | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| P49356 | FNTB_HUMAN | Homo sapiens | Protein farnesyltransferase subunit beta |
