PDB Information

PDB1RV1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.
Vassilev, L.T., Vu, B.T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., Fotouhi, N., Liu, E.A.
Science
HeaderLigase
Released2003-12-12
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
1rv1A00 05 Mar, 2006 1.10.245.10 Assigned
1rv1B00 05 Mar, 2006 1.10.245.10 Assigned
1rv1C00 05 Mar, 2006 1.10.245.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
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