PDB Information

PDB1O5F
MethodX-RAY DIFFRACTION
Host OrganismPichia pastoris
Gene SourceHomo sapiens
Primary Citation
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
Katz, B.A., Luong, C., Ho, J.D., Somoza, J.R., Gjerstad, E., Tang, J., Williams, S.R., Verner, E., Mackman, R.L., Young, W.B., Sprengeler, P.A., Chan, H., Mortara, K., Janc, J.W., McGrath, M.E.
J.Mol.Biol.
HeaderSerine Protease, Hydrolase
Released2003-09-09
Resolution1.780
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
L 05 Mar, 2006 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
1o5fH01 01 Nov, 2006 2.40.10.10 Assigned
1o5fH02 01 Nov, 2006 2.40.10.10 Assigned
1o5fL00 08 Mar, 2006 3.10.250.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P05981 HEPS_HUMAN Homo sapiens Serine protease hepsin
P05981 HEPS_HUMAN Homo sapiens Serine protease hepsin