PDB Information

PDB1O5D
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
Katz, B.A., Luong, C., Ho, J.D., Somoza, J.R., Gjerstad, E., Tang, J., Williams, S.R., Verner, E., Mackman, R.L., Young, W.B., Sprengeler, P.A., Chan, H., Mortara, K., Janc, J.W., McGrath, M.E.
J.Mol.Biol.
HeaderBlood Clotting, Hydrolase
Released2003-09-09
Resolution2.050
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
L 05 Mar, 2006 Chopped
T 05 Mar, 2006 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
1o5dH01 05 Mar, 2006 2.40.10.10 Assigned
1o5dH02 05 Mar, 2006 2.40.10.10 Assigned
1o5dL01 05 Mar, 2006 2.10.25.10 Assigned
1o5dL02 05 Mar, 2006 2.10.25.10 Assigned
1o5dT00 05 Mar, 2006 2.60.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P13726 TF_HUMAN Homo sapiens Tissue factor
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
CATH-Gene3D is a Global Biodata Core Resource Learn more...