PDB Information

PDB1MZC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Dual Protein Farnesyltransferase-Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents.
DeSolms, S.J., Ciccarone, T.M., MacTough, S.C., Shaw, A.W., Buser, C.A., Ellis-Hutchings, M., Fernandes, C., Hamilton, K.A., Huber, H.E., Kohl, N.E., Lobell, R.B., Robinson, R.G., Tsou, N.N., Walsh, E.S., Graham, S.L., Beese, L.S., Taylor, J.S.
J.Med.Chem.
HeaderTransferase
Released2002-10-07
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1mzcA00 05 Mar, 2006 1.25.40.120 Assigned
1mzcB00 05 Mar, 2006 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49354 FNTA_HUMAN Homo sapiens Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
P49356 FNTB_HUMAN Homo sapiens Protein farnesyltransferase subunit beta
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