PDB 1hvy

PDB Links
Overview

PDB Information

PDB	1HVY
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug Phan, J., Koli, S., Minor, W., Dunlap, R.B., Berger, S.H., Lebioda, L. Biochemistry
Header	Transferase
Released	2001-01-08
Resolution	1.900
CATH Insert Date	05 Mar, 2006

PDB Images (9)

Image of CATH 1hvy

1hvy

PDB 1hvy

Image of CATH 1hvyA

1hvyA

PDB Chain 1hvyA

Image of CATH 1hvyB

1hvyB

PDB Chain 1hvyB

Image of CATH 1hvyC

1hvyC

PDB Chain 1hvyC

Image of CATH 1hvyD

1hvyD

PDB Chain 1hvyD

Image of CATH 1hvyA00

1hvyA00

CATH Domain 1hvyA00

Image of CATH 1hvyB00

1hvyB00

CATH Domain 1hvyB00

Image of CATH 1hvyC00

1hvyC00

CATH Domain 1hvyC00

Image of CATH 1hvyD00

1hvyD00

CATH Domain 1hvyD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped
C	05 Mar, 2006	Chopped
D	05 Mar, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1hvyA00	05 Mar, 2006	3.30.572.10	Assigned
1hvyB00	05 Mar, 2006	3.30.572.10	Assigned
1hvyC00	05 Mar, 2006	3.30.572.10	Assigned
1hvyD00	05 Mar, 2006	3.30.572.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P04818	TYSY_HUMAN	Homo sapiens	Thymidylate synthase
P04818	TYSY_HUMAN	Homo sapiens	Thymidylate synthase
P04818	TYSY_HUMAN	Homo sapiens	Thymidylate synthase
P04818	TYSY_HUMAN	Homo sapiens	Thymidylate synthase