PDB Information

PDB1EF3
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography.
Oka, M., Matsumoto, Y., Sugiyama, S., Tsuruta, N., Matsushima, M.
J.Med.Chem.
HeaderOxidoreductase
Released2000-02-06
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1ef3A00 05 Mar, 2006 3.20.20.100 Assigned
1ef3B00 05 Mar, 2006 3.20.20.100 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15121 ALDR_HUMAN Homo sapiens Aldo-keto reductase family 1 member B1
P15121 ALDR_HUMAN Homo sapiens Aldo-keto reductase family 1 member B1
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