PDB Information

PDB1DIG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.
Biochemistry
HeaderOxidoreductase,Hydrolase
Released1999-11-29
Resolution2.200
CATH Insert Date05 Mar, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1digA01 05 Mar, 2006 3.40.50.720 Assigned
1digA02 05 Mar, 2006 3.40.50.10860 Assigned
1digB01 05 Mar, 2006 3.40.50.720 Assigned
1digB02 05 Mar, 2006 3.40.50.10860 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11586 C1TC_HUMAN Homo sapiens C-1-tetrahydrofolate synthase, cytoplasmic
P11586 C1TC_HUMAN Homo sapiens C-1-tetrahydrofolate synthase, cytoplasmic
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