PDB Information

PDB1B0F
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones.
Cregge, R.J., Durham, S.L., Farr, R.A., Gallion, S.L., Hare, C.M., Hoffman, R.V., Janusz, M.J., Kim, H.O., Koehl, J.R., Mehdi, S., Metz, W.A., Peet, N.P., Pelton, J.T., Schreuder, H.A., Sunder, S., Tardif, C.
J.Med.Chem.
HeaderHydrolase
Released1998-11-09
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1b0fA01 05 Mar, 2006 2.40.10.10 Assigned
1b0fA02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08246 ELNE_HUMAN Homo sapiens Neutrophil elastase
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