PDB Information

PDB1AYU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design of potent and selective human cathepsin K inhibitors that span the active site.
Thompson, S.K., Halbert, S.M., Bossard, M.J., Tomaszek, T.A., Levy, M.A., Zhao, B., Smith, W.W., Abdel-Meguid, S.S., Janson, C.A., D'Alessio, K.J., McQueney, M.S., Amegadzie, B.Y., Hanning, C.R., DesJarlais, R.L., Briand, J., Sarkar, S.K., Huddleston, M.J., Ijames, C.F., Carr, S.A., Garnes, K.T., Shu, A., Heys, J.R., Bradbeer, J., Zembryki, D., Lee-Rykaczewski, L., James, I.E., Lark, M.W., Drake, F.H., Gowen, M., Gleason, J.G., Veber, D.F.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase
Released1997-11-10
Resolution2.200
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1ayuA00 05 Mar, 2006 3.90.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43235 CATK_HUMAN Homo sapiens Cathepsin K
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