PDB Information

PDB1AFE
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study.
De Simone, G., Balliano, G., Milla, P., Gallina, C., Giordano, C., Tarricone, C., Rizzi, M., Bolognesi, M., Ascenzi, P.
J.Mol.Biol.
HeaderHydrolase/Hydrolase Inhibitor
Released1997-03-06
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
L 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1afeH01 05 Mar, 2006 2.40.10.10 Assigned
1afeH02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P01050 HIRV1_HIRME Hirudo medicinalis Hirudin variant-1
P00734 THRB_HUMAN Homo sapiens Prothrombin