PDB Information

PDB1A5H
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors.
Renatus, M., Bode, W., Huber, R., Sturzebecher, J., Prasa, D., Fischer, S., Kohnert, U., Stubbs, M.T.
J.Biol.Chem.
HeaderHydrolase
Released1998-02-17
Resolution2.900
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Rejected
D 05 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1a5hA01 05 Mar, 2006 2.40.10.10 Assigned
1a5hA02 05 Mar, 2006 2.40.10.10 Assigned
1a5hB01 05 Mar, 2006 2.40.10.10 Assigned
1a5hB02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00750 TPA_HUMAN Homo sapiens Tissue-type plasminogen activator
P00750 TPA_HUMAN Homo sapiens Tissue-type plasminogen activator
P00750 TPA_HUMAN Homo sapiens Tissue-type plasminogen activator
P00750 TPA_HUMAN Homo sapiens Tissue-type plasminogen activator