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CATH Superfamily 1.25.40.320

Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain

According to the literature, members of the structural domains which comprise this superfamily correspond to the structure of the C-terminal domain of M1 peptidases which include LTA-4. The interface of the domains that constitute this protein form a cavity where the active Zn2+ site is found.

GO Diversity

Unique GO annotations
55 Unique GO terms

EC Diversity

Unique EC annotations
4 Unique EC terms

Species Diversity

Unique species annotations
1923 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 74
Domain clusters (>95% seq id): 4
Domain clusters (>35% seq id): 3
Unique PDBs: 66
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 13
Function
Unique EC: 4
Unique GO: 55
Taxonomy
Unique Species: 1923