# STOCKHOLM 1.0
#=GF ID 3.20.20.220/FF/000018
#=GF DE Methylenetetrahydrofolate reductase
#=GF AC 3.20.20.220/FF/000018
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 41.290
#=GS Q17693/57-348      AC Q17693
#=GS Q17693/57-348      OS Caenorhabditis elegans
#=GS Q17693/57-348      DE Probable methylenetetrahydrofolate reductase
#=GS Q17693/57-348      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS Q17693/57-348      DR EC; 1.5.1.20; 
#=GS H3F1N6/6-302       AC H3F1N6
#=GS H3F1N6/6-302       OS Pristionchus pacificus
#=GS H3F1N6/6-302       DE Methylenetetrahydrofolate reductase
#=GS H3F1N6/6-302       DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; 
#=GS A8XGS0/36-277      AC A8XGS0
#=GS A8XGS0/36-277      OS Caenorhabditis briggsae
#=GS A8XGS0/36-277      DE Protein CBG12961
#=GS A8XGS0/36-277      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS A0A2H2I9S3/30-321  AC A0A2H2I9S3
#=GS A0A2H2I9S3/30-321  OS Caenorhabditis japonica
#=GS A0A2H2I9S3/30-321  DE Methylenetetrahydrofolate reductase
#=GS A0A2H2I9S3/30-321  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis japonica; 
#=GS A0A2G5V0X0/58-349  AC A0A2G5V0X0
#=GS A0A2G5V0X0/58-349  OS Caenorhabditis nigoni
#=GS A0A2G5V0X0/58-349  DE Methylenetetrahydrofolate reductase
#=GS A0A2G5V0X0/58-349  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A261C7W8/57-348  AC A0A261C7W8
#=GS A0A261C7W8/57-348  OS Caenorhabditis latens
#=GS A0A261C7W8/57-348  DE Methylenetetrahydrofolate reductase
#=GS A0A261C7W8/57-348  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; 
#=GS A0A1I7T4S0/57-348  AC A0A1I7T4S0
#=GS A0A1I7T4S0/57-348  OS Caenorhabditis tropicalis
#=GS A0A1I7T4S0/57-348  DE Methylenetetrahydrofolate reductase
#=GS A0A1I7T4S0/57-348  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis tropicalis; 
#=GS E3MN18/57-348      AC E3MN18
#=GS E3MN18/57-348      OS Caenorhabditis remanei
#=GS E3MN18/57-348      DE Methylenetetrahydrofolate reductase
#=GS E3MN18/57-348      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; 
#=GS A8XGR9/87-409      AC A8XGR9
#=GS A8XGR9/87-409      OS Caenorhabditis briggsae
#=GS A8XGR9/87-409      DE Methylenetetrahydrofolate reductase
#=GS A8XGR9/87-409      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS K7HSL3/36-327      AC K7HSL3
#=GS K7HSL3/36-327      OS Caenorhabditis japonica
#=GS K7HSL3/36-327      DE Methylenetetrahydrofolate reductase
#=GS K7HSL3/36-327      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis japonica; 
#=GS A0A2G5V0V9/37-328  AC A0A2G5V0V9
#=GS A0A2G5V0V9/37-328  OS Caenorhabditis nigoni
#=GS A0A2G5V0V9/37-328  DE Methylenetetrahydrofolate reductase
#=GS A0A2G5V0V9/37-328  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GS A0A2G5V1N2/37-328  AC A0A2G5V1N2
#=GS A0A2G5V1N2/37-328  OS Caenorhabditis nigoni
#=GS A0A2G5V1N2/37-328  DE Methylenetetrahydrofolate reductase
#=GS A0A2G5V1N2/37-328  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GF SQ 12
Q17693/57-348              -----LLHERIERLIDEKQQFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELED---THQFRALDMIRWIREEYGNYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVITQLFFEAETFEKFVRDCREIGITQPIIPGIMPI-------MGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKS----------
H3F1N6/6-302               ---------SITK---------SITVF--QTANGVANFYTRLDRYKEGDPLSMVVRATNVRASGVVYNGRRFSANLTRETSSSSIAAGCLDYCRMDTMLHMTCTQYTKEQTIAHLEQSKRIGLRNILALRGDLPPN----------------TSSDAPVIKPKYMALDMIKWIKEEFGDYFTIACSGYPLGHPEAVSYAEDLKYLKAKVDAGAQLIVTQLFFEAEAYERFVRDCREMGITVPILPGIMPIQSCEKIRQSYDSIRRIAQLSQLAIPDSILADLEPIKHDDDAVRNYGRHRAIEMCRRILSNGTAPAIHMYTMNREGSCREILQE----------
A8XGS0/36-277              ----ELLHERIERLIEEKTPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELED---TNQFRALDMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIGITKPIIPGIMPI-------MGYESIKRIAKLSQLEIPEHXXLDA-------------------------------------------------------------
A0A2H2I9S3/30-321          -----LLHERIERLIEEKQQFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELQD---THQFRALDIIRWIREEYGDYFSIACAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFYEAETFENFVRDCREIGITKPIIPGIMPI-------MAYESTIRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTEKCIEMCKRLLGNGSAPSVHMYTMNREGSIREILKA----------
A0A2G5V0X0/58-349          -----LLHERIERLIDEKTPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELED---TNQFRALDMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIGITKPIIPGIMPI-------MGYESIKRIAKLSQLEIPDHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKA----------
A0A261C7W8/57-348          -----LLHERIERLIDEKQPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELQD---THQFRALDMIRWIREEYGSYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVITQLFFEPETFEKFVRDCREIGITQPIIPGIMPI-------MGYESIKRIATLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHLYTMNREGSIREILKA----------
A0A1I7T4S0/57-348          -----LLHERIERLIDEKQAFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELED---THQFRALDMIRWIREEYGNYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVITQLFFEAETFEKFVRDCREIGITKPIIPGIMPI-------MGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKS----------
E3MN18/57-348              -----LLHERIERLIDEKQPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELQD---THQFRALDMIRWIREEYGSYFSIGCAGYPLGHPQAPSYKADLMYLKAKCDAGANFVITQLFFEPETFEKFVRDCREIGITQPIIPGIMPI-------MGYESIKRIATLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIAMCRRLLDNGSAPSIHLYTMNREGSIREILKA----------
A8XGR9/87-409              LKNYELLHERIERLIEEKTPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGVCCGIVSNSFFIFMFQTELED---TNQFRALDMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIGITKPIIPGIMPI-------MGYESIKRIAKLSQLEIPEHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKALGLWKLEGDR
K7HSL3/36-327              -----LLHERIERLIEEKQQFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELQD---THQFRALDIIRWIREEYGDYFSIACAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFYEAETFENFVRDCREIGITKPIIPGIMPI-------MAYESTIRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTEKCIEMCKRLLGNGSAPSVHMYTMNREGSIREILKA----------
A0A2G5V0V9/37-328          -----LLHERIERLIDEKTPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELED---TNQFRALDMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIGITKPIIPGIMPI-------MGYESIKRIAKLSQLEIPDHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKA----------
A0A2G5V1N2/37-328          -----LLHERIERLIDEKTPFFSLEFFPPRFVNGVPNFLERVERLSEGG--SVFVDMT--------WHMGSDPANIDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPG----------------TELED---TNQFRALDMIRWIREEYGDYFSIGCAGYPLGHPQAPSYKADLQYLKAKCDAGANFVITQLFFEPETFEKFVADCREIGITKPIIPGIMPI-------MGYESIKRIAKLSQLEIPDHILEDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGSAPSIHLYTMNREGSIREILKA----------
#=GC scorecons             0000055556967554553355976695576699969966977966996009769669000000006656656996676999999996699996799999999699696697699996967999699999999996000000000000000096656000647769997979979979699696969999999796996699499999699996777999989597796995999979994997999999000000065979759995999969956663966666666666446644546466564636646645646666666636666430000000000
#=GC scorecons_70          __________*_*_________**_**__*_*******__****__***__****__*________**_*__***__*_*********_*******************_***_******_****************________________*_________**_******************_***********_**__**_*****_**************_*******_********_*********_________****_***_****_**_____**_____________________________________________________________
#=GC scorecons_80          __________*_*_________*___*_____***_**__*_**__**___*__*__*_______________**__*_********__****__********_**_*__*__****_*_****_**********_________________*__________*_*************_**_*_*_*******_*_**__**_*****_****__********_*_**_**_********_**_******_________****_***_****_**_____*______________________________________________________________
#=GC scorecons_90          __________*___________*___*_____***_**__*__*__**___*__*__*_______________**____********__****__********_**_*__*__****_*__***_**********_________________*____________***_*_**_**_*_**_*_*_*******_*_**__**_*****_****____******_*__*_**_****_***_**_******_________*_*__***_****_**_____*______________________________________________________________
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