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CATH Superfamily 2.40.50.150

RNA polymerase II, Rpb2 subunit, wall domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: RNA polymerase II, Rpb2 subunit, wall domain

RNA polymerase II (Pol II) is responsible for all mRNA synthesis in eukaryotes. Pol II transcription is the first step in gene expression and a focal point of cell regulation. Pol II comprises 12 subunits, with a total mass of more than 0.5 MD. This entry represents the wall domain of the subunit Rpb2 PMID:11313498. It exhibits an OB fold.

GO Diversity

Unique GO annotations
72 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
15400 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 197
Domain clusters (>95% seq id): 9
Domain clusters (>35% seq id): 3
Unique PDBs: 155
Alignments
Structural Clusters (5A): 2
Structural Clusters (9A): 1
FunFam Clusters: 46
Function
Unique EC: 1
Unique GO: 72
Taxonomy
Unique Species: 15400
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