The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: CYtochrome P450 family

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Docosahexaenoic acid omega-hydroxylase. [EC: 1.14.14.79]
Docosahexaenoate + [reduced NADPH--hemoprotein reductase] + O(2) = 22-hydroxydocosahexaenoate + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein isolated from human eye tissue.
  • Defects in the enzyme are associated with Bietti crystalline corneoretinal dystrophy.
  • The enzyme also produces some 21-hydroxydocosahexaenoate.
  • Acts in a similar way on icosapentaenoic acid.
  • Formerly EC 1.14.13.199.
7 A2RRT9 B2RSR0 B2RSR0 Q5RCN6 Q6ZWL3 Q9DBW0 Q9DBW0
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