CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.3450
Functional Family Alkylglycerone-phosphate synthase

Enzyme Information

2.5.1.26
Alkylglycerone-phosphate synthase.
based on mapping to UniProt P97275
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
-!- The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.

UniProtKB Entries (1)

P97275
ADAS_CAVPO
Cavia porcellus
Alkyldihydroxyacetonephosphate synthase, peroxisomal

PDB Structure

PDB 4BBY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Proc.Natl.Acad.Sci.USA
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