CATH Classification

Domain Context

CATH Clusters

Superfamily Macrophage Migration Inhibitory Factor
Functional Family D-dopachrome decarboxylase

Enzyme Information

4.1.1.84
D-dopachrome decarboxylase.
based on mapping to UniProt P30046
D-dopachrome = 5,6-dihydroxyindole + CO(2).
-!- Specific for D-dopachrome as substrate. -!- L-dopachrome, L- or D-alpha-methyldopachrome and dopaminochrome do not act as substrates (see also EC 5.3.3.12).

UniProtKB Entries (1)

P30046
DOPD_HUMAN
Homo sapiens
D-dopachrome decarboxylase

PDB Structure

PDB 3KAN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of D-DOPACHROME TAUTOMERASE (D-DT)/MACROPHAGE MIGRATION INHIBITORY FACTOR 2 (MIF2) COMPLEXED WITH INHIBITOR 4-IPP
Zierow, S., Lolis, E.
To be Published
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