CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.60 | Lipoxygenase-1 |
|
2.60.60.20 | PLAT/LH2 domain |
Domain Context
CATH Clusters
| Superfamily | PLAT/LH2 domain |
| Functional Family |
Enzyme Information
| 1.13.11.58 |
Linoleate 9S-lipoxygenase.
based on mapping to UniProt P24095
Linoleate + O(2) = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
-!- A common plant lipoxygenase that oxidizes linoleate and alpha- linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C(9) position with (S)- configuration. -!- The enzyme plays a physiological role during the early stages of seedling growth. -!- The enzyme from Arabidopsis thaliana shows comparable activity toward linoleate and linolenate. -!- EC 1.13.11.12 catalyzes a similar reaction at another position of these fatty acids.
|
UniProtKB Entries (1)
| P24095 |
LOXX_SOYBN
Glycine max
Seed linoleate 9S-lipoxygenase
|
PDB Structure
| PDB | 2IUK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins
|
