# STOCKHOLM 1.0 #=GF ID 4.10.400.10/FF/000149 #=GF DE enteropeptidase isoform X2 #=GF AC 4.10.400.10/FF/000149 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 81.474 #=GS P98073/639-678 AC P98073 #=GS P98073/639-678 OS Homo sapiens #=GS P98073/639-678 DE Enteropeptidase #=GS P98073/639-678 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS P98073/639-678 DR GO; GO:0005515; GO:0005903; #=GS P98073/639-678 DR EC; 3.4.21.9; #=GS P98072/655-692 AC P98072 #=GS P98072/655-692 OS Bos taurus #=GS P98072/655-692 DE Enteropeptidase #=GS P98072/655-692 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS P98072/655-692 DR GO; GO:0016020; GO:0032023; GO:0044256; #=GS P98072/655-692 DR EC; 3.4.21.9; #=GS Q6X0I2/31-78 AC Q6X0I2 #=GS Q6X0I2/31-78 OS Solenopsis invicta #=GS Q6X0I2/31-78 DE Vitellogenin receptor #=GS Q6X0I2/31-78 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Aculeata; Formicoidea; Formicidae; Myrmicinae; Solenopsidini; Solenopsis; Solenopsis invicta; #=GS Q6X0I2/31-78 DR GO; GO:0006898; GO:0038024; #=GS P97435/684-721 AC P97435 #=GS P97435/684-721 OS Mus musculus #=GS P97435/684-721 DE Enteropeptidase #=GS P97435/684-721 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS P97435/684-721 DR EC; 3.4.21.9; #=GS E9Q6Y6/669-706 AC E9Q6Y6 #=GS E9Q6Y6/669-706 OS Mus musculus #=GS E9Q6Y6/669-706 DE Enteropeptidase #=GS E9Q6Y6/669-706 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS Q8CAN9/393-430 AC Q8CAN9 #=GS Q8CAN9/393-430 OS Mus musculus #=GS Q8CAN9/393-430 DE Uncharacterized protein #=GS Q8CAN9/393-430 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS W4XVR8/546-588 AC W4XVR8 #=GS W4XVR8/546-588 OS Strongylocentrotus purpuratus #=GS W4XVR8/546-588 DE Uncharacterized protein #=GS W4XVR8/546-588 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS A0A1D5P7Y3/677-714 AC A0A1D5P7Y3 #=GS A0A1D5P7Y3/677-714 OS Gallus gallus #=GS A0A1D5P7Y3/677-714 DE Uncharacterized protein #=GS A0A1D5P7Y3/677-714 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus; Gallus gallus; #=GS F6QQY8/419-457 AC F6QQY8 #=GS F6QQY8/419-457 OS Xenopus tropicalis #=GS F6QQY8/419-457 DE Transmembrane serine protease 15 #=GS F6QQY8/419-457 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS F6PXZ4/645-682 AC F6PXZ4 #=GS F6PXZ4/645-682 OS Ornithorhynchus anatinus #=GS F6PXZ4/645-682 DE Transmembrane serine protease 15 #=GS F6PXZ4/645-682 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GS P98074/654-691 AC P98074 #=GS P98074/654-691 OS Sus scrofa #=GS P98074/654-691 DE Enteropeptidase #=GS P98074/654-691 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS P98074/654-691 DR EC; 3.4.21.9; #=GS A0A2Y9NB90/639-676 AC A0A2Y9NB90 #=GS A0A2Y9NB90/639-676 OS Delphinapterus leucas #=GS A0A2Y9NB90/639-676 DE enteropeptidase isoform X2 #=GS A0A2Y9NB90/639-676 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Monodontidae; Delphinapterus; Delphinapterus leucas; #=GS M3WXF8/639-677 AC M3WXF8 #=GS M3WXF8/639-677 OS Felis catus #=GS M3WXF8/639-677 DE Uncharacterized protein #=GS M3WXF8/639-677 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis; Felis catus; #=GS F7AVP5/639-677 AC F7AVP5 #=GS F7AVP5/639-677 OS Equus caballus #=GS F7AVP5/639-677 DE Transmembrane serine protease 15 #=GS F7AVP5/639-677 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Perissodactyla; Equidae; Equus; Equus; Equus caballus; #=GS S9X2A7/511-548 AC S9X2A7 #=GS S9X2A7/511-548 OS Camelus ferus #=GS S9X2A7/511-548 DE Enteropeptidase #=GS S9X2A7/511-548 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Tylopoda; Camelidae; Camelus; Camelus ferus; #=GS A0A091DMY5/469-507 AC A0A091DMY5 #=GS A0A091DMY5/469-507 OS Fukomys damarensis #=GS A0A091DMY5/469-507 DE Enteropeptidase #=GS A0A091DMY5/469-507 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys; Fukomys damarensis; #=GS A0A3Q7S6H8/639-677 AC A0A3Q7S6H8 #=GS A0A3Q7S6H8/639-677 OS Vulpes vulpes #=GS A0A3Q7S6H8/639-677 DE enteropeptidase #=GS A0A3Q7S6H8/639-677 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes; Vulpes vulpes; #=GS A0A2Y9SK32/639-677 AC A0A2Y9SK32 #=GS A0A2Y9SK32/639-677 OS Physeter catodon #=GS A0A2Y9SK32/639-677 DE enteropeptidase #=GS A0A2Y9SK32/639-677 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Physeteridae; Physeter; Physeter catodon; #=GS A0A2Y9JCA4/654-692 AC A0A2Y9JCA4 #=GS A0A2Y9JCA4/654-692 OS Enhydra lutris kenyoni #=GS A0A2Y9JCA4/654-692 DE enteropeptidase #=GS A0A2Y9JCA4/654-692 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Lutrinae; Enhydra; Enhydra lutris; Enhydra lutris kenyoni; #=GS A0A340Y5N2/638-675 AC A0A340Y5N2 #=GS A0A340Y5N2/638-675 OS Lipotes vexillifer #=GS A0A340Y5N2/638-675 DE enteropeptidase isoform X2 #=GS A0A340Y5N2/638-675 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Lipotidae; Lipotes; Lipotes vexillifer; #=GS W5Q241/658-695 AC W5Q241 #=GS W5Q241/658-695 OS Ovis aries #=GS W5Q241/658-695 DE Enteropeptidase #=GS W5Q241/658-695 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Ovis; Ovis aries; #=GS M3YH42/688-726 AC M3YH42 #=GS M3YH42/688-726 OS Mustela putorius furo #=GS M3YH42/688-726 DE Transmembrane serine protease 15 #=GS M3YH42/688-726 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Mustelinae; Mustela; Mustela putorius; Mustela putorius furo; #=GS F1PAU3/657-694 AC F1PAU3 #=GS F1PAU3/657-694 OS Canis lupus familiaris #=GS F1PAU3/657-694 DE Transmembrane serine protease 15 #=GS F1PAU3/657-694 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis; Canis lupus; Canis lupus familiaris; #=GS D4A911/475-513 AC D4A911 #=GS D4A911/475-513 OS Rattus norvegicus #=GS D4A911/475-513 DE Transmembrane serine protease 15 #=GS D4A911/475-513 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS A0A452EEU9/640-679 AC A0A452EEU9 #=GS A0A452EEU9/640-679 OS Capra hircus #=GS A0A452EEU9/640-679 DE Uncharacterized protein #=GS A0A452EEU9/640-679 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Capra; Capra hircus; #=GS A0A2I3FTJ2/610-649 AC A0A2I3FTJ2 #=GS A0A2I3FTJ2/610-649 OS Nomascus leucogenys #=GS A0A2I3FTJ2/610-649 DE Uncharacterized protein #=GS A0A2I3FTJ2/610-649 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hylobatidae; Nomascus; Nomascus leucogenys; #=GS G3QEB0/639-678 AC G3QEB0 #=GS G3QEB0/639-678 OS Gorilla gorilla gorilla #=GS G3QEB0/639-678 DE Enteropeptidase #=GS G3QEB0/639-678 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Gorilla; Gorilla gorilla; Gorilla gorilla gorilla; #=GS H2QKV6/639-678 AC H2QKV6 #=GS H2QKV6/639-678 OS Pan troglodytes #=GS H2QKV6/639-678 DE Enteropeptidase #=GS H2QKV6/639-678 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A2R9A1D2/621-658 AC A0A2R9A1D2 #=GS A0A2R9A1D2/621-658 OS Pan paniscus #=GS A0A2R9A1D2/621-658 DE Uncharacterized protein #=GS A0A2R9A1D2/621-658 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS A0A2Y9NLK0/654-691 AC A0A2Y9NLK0 #=GS A0A2Y9NLK0/654-691 OS Delphinapterus leucas #=GS A0A2Y9NLK0/654-691 DE Enteropeptidase #=GS A0A2Y9NLK0/654-691 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Monodontidae; Delphinapterus; Delphinapterus leucas; #=GS F1SHP8/654-691 AC F1SHP8 #=GS F1SHP8/654-691 OS Sus scrofa #=GS F1SHP8/654-691 DE Enteropeptidase #=GS F1SHP8/654-691 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS A0A287AAQ8/639-676 AC A0A287AAQ8 #=GS A0A287AAQ8/639-676 OS Sus scrofa #=GS A0A287AAQ8/639-676 DE Enteropeptidase #=GS A0A287AAQ8/639-676 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS G1QP44/622-661 AC G1QP44 #=GS G1QP44/622-661 OS Nomascus leucogenys #=GS G1QP44/622-661 DE Uncharacterized protein #=GS G1QP44/622-661 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hylobatidae; Nomascus; Nomascus leucogenys; #=GS A0A2R9A5N9/621-660 AC A0A2R9A5N9 #=GS A0A2R9A5N9/621-660 OS Pan paniscus #=GS A0A2R9A5N9/621-660 DE Uncharacterized protein #=GS A0A2R9A5N9/621-660 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS A0A452DHT9/655-692 AC A0A452DHT9 #=GS A0A452DHT9/655-692 OS Bos taurus #=GS A0A452DHT9/655-692 DE Enteropeptidase #=GS A0A452DHT9/655-692 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS A0A452DKK8/628-665 AC A0A452DKK8 #=GS A0A452DKK8/628-665 OS Bos taurus #=GS A0A452DKK8/628-665 DE Enteropeptidase #=GS A0A452DKK8/628-665 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS A0A3Q1M3Y1/643-680 AC A0A3Q1M3Y1 #=GS A0A3Q1M3Y1/643-680 OS Bos taurus #=GS A0A3Q1M3Y1/643-680 DE Enteropeptidase #=GS A0A3Q1M3Y1/643-680 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS A0A452EEP0/643-682 AC A0A452EEP0 #=GS A0A452EEP0/643-682 OS Capra hircus #=GS A0A452EEP0/643-682 DE Uncharacterized protein #=GS A0A452EEP0/643-682 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Capra; Capra hircus; #=GS A0A340Y137/653-690 AC A0A340Y137 #=GS A0A340Y137/653-690 OS Lipotes vexillifer #=GS A0A340Y137/653-690 DE enteropeptidase isoform X1 #=GS A0A340Y137/653-690 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Lipotidae; Lipotes; Lipotes vexillifer; #=GS F6PY06/657-694 AC F6PY06 #=GS F6PY06/657-694 OS Ornithorhynchus anatinus #=GS F6PY06/657-694 DE Transmembrane serine protease 15 #=GS F6PY06/657-694 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GF SQ 40 P98073/639-678 -IPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEA-DCV------ P98072/655-692 -IPEPCKEDNFQCKDGECIPLVNLCDGFPHCKDGSDEA-H-------- Q6X0I2/31-78 LKKTKCEDGYFQCNSGECIPVDKKCDYIDHCIDGSDEDFECDHLDEKS P97435/684-721 -IPEPCQDDEFQCKDGNCIPLGNLCDSYPHCRDGSDEA-S-------- E9Q6Y6/669-706 -IPEPCQDDEFQCKDGNCIPLGNLCDSYPHCRDGSDEA-S-------- Q8CAN9/393-430 -IPEPCQDDEFQCKDGNCIPLGNLCDSYPHCRDGSDEA-S-------- W4XVR8/546-588 TTSSPCRNNFFQCGSGECIPVSFFCDFIKHCQDGADEE-KCNYP---- A0A1D5P7Y3/677-714 ---GACAPEEYQCQSGHCIPLDNLCDKVPQCEDGSDEA-KCM------ F6QQY8/419-457 GMPEPCNSTSFQCGSGECIPNTAVCDKHRDCDDGTDER-H-------- F6PXZ4/645-682 -MEEPCQGGGFRCGSGECIAAEHLCDGHRHCQDGSDEA-E-------- P98074/654-691 -IPEPCKEDNFQCENGECVLLVNLCDGFSHCKDGSDEA-H-------- A0A2Y9NB90/639-676 -IPEPCKEDNFQCENGECVPLVNLCDSFPHCKDGSDEA-H-------- M3WXF8/639-677 -IPEPCKEDQFQCKNGECIPLVNLCDSHLHCKDGSDEA-HC------- F7AVP5/639-677 -IPEPCKEDNFQCKNGECVPLVNLCDGLPHCPDGSDEA-HC------- S9X2A7/511-548 -IPEPCKEDNFQCKDGECVPLVNLCDGFPHCKDGSDEA-H-------- A0A091DMY5/469-507 -IPEPCKEDEFQCKNGECIPLVNLCDSHPHCGDGSDEA-HC------- A0A3Q7S6H8/639-677 -IPEPCKEDDFQCKNGECVPLVNLCDGLPHCKDGSDEA-HC------- A0A2Y9SK32/639-677 -IPEPCKEDNFQCKNGECIPLVNLCDSFPHCKDGSDEA-HC------- A0A2Y9JCA4/654-692 -IPEPCKEDYFQCKNGECVPLVNLCDGLLHCKDGSDEA-HC------- A0A340Y5N2/638-675 -IPEPCKEDNFQCKNGECVPLVNLCDSFPHCKDGSDEA-H-------- W5Q241/658-695 -IPEPCKEDNFQCKNGECIPLVNLCDGFPHCKDGSDEA-P-------- M3YH42/688-726 -IPEPCKEDYFQCKNGECVPLVNLCDGLLHCKDGSDEA-HC------- F1PAU3/657-694 -V-EPCKEDDFQCKNGECVPLVNLCDGLPHCKDGSDEA-HC------- D4A911/475-513 -IPQPCQDDEFQCKDGNCIPMGNLCDSYQHCSDGSDEA-HC------- A0A452EEU9/640-679 -IPQPCKEDNFQCKNGECIPLVNLCDGFPHCKDGSDEA-PCV------ A0A2I3FTJ2/610-649 -IPEPCKEDNFQCKNGECVPLVNLCDGHLHCEDGSDEA-DCV------ G3QEB0/639-678 -IPEPCKEDHFQCKNGECVPLVNLCDGHLHCEDGSDEA-DCV------ H2QKV6/639-678 -IPEPCKEDHFQCKNGECVPLVNLCDGHLHCEDGSDEA-DCV------ A0A2R9A1D2/621-658 -IPDPCKEDHFQCKNGECVPLVNLCDGHLHCEDGSDEA-D-------- A0A2Y9NLK0/654-691 -IPEPCKEDNFQCENGECVPLVNLCDSFPHCKDGSDEA-H-------- F1SHP8/654-691 -IPEPCKEDNFQCENGECVLLVNLCDGFSHCKDGSDEA-H-------- A0A287AAQ8/639-676 -IPEPCKEDNFQCENGECVLLVNLCDGFSHCKDGSDEA-H-------- G1QP44/622-661 -IPEPCKEDNFQCKNGECVPLVNLCDGHLHCEDGSDEA-DCV------ A0A2R9A5N9/621-660 -IPDPCKEDHFQCKNGECVPLVNLCDGHLHCEDGSDEA-DCV------ A0A452DHT9/655-692 -IPEPCKEDNFQCKDGECIPLVNLCDGFPHCKDGSDEA-H-------- A0A452DKK8/628-665 -IPEPCKEDNFQCKDGECIPLVNLCDGFPHCKDGSDEA-H-------- A0A3Q1M3Y1/643-680 -IPEPCKEDNFQCKDGECIPLVNLCDGFPHCKDGSDEA-H-------- A0A452EEP0/643-682 -IPQPCKEDNFQCKNGECIPLVNLCDGFPHCKDGSDEA-PCV------ A0A340Y137/653-690 -IPEPCKEDNFQCKNGECVPLVNLCDSFPHCKDGSDEA-H-------- F6PY06/657-694 -MEEPCQGGGFRCGSGECIAAEHLCDGHRHCQDGSDEA-E-------- #=GC scorecons 055679556388955979776467994448949979960420000000 #=GC scorecons_70 ___***__*_***__*****__****___**_******__________ #=GC scorecons_80 ____**____***__*****____**___**_*****___________ #=GC scorecons_90 _____*____***__*_*______**____*_**_**___________ //